Summary
"Hot pixels" and/or "Wild pixels" can be fixed using the Noise Reduction Tool in Capture One.
In-Depth
The following image is an example of what a hot pixel is.
This can be fixed using the Noise Reduction Tool as seen in the result below:
Settings used in the Noise Reduction Tool:
It is usually enough to set the "Noise Reductions" - "Single Pixel" slider to 1 (instead of 0).
If there are remaining pixel points these can be removed with the Spot Tool for better overall results.
General tips to avoid hot pixels with P65+/P40+ and IQ units
Latency: In general "Normal Latency" should be used as "Zero Latency" keeps the back in a 'ready state' mode where the sensor and power boards inside the back remain charged and generates heat. This addition of heat can cause hot pixels in the images on long exposures. We therefore recommend that the back's Auto Power Down function is enabled and used when the back is in Zero Latency or the user turn off the back and camera when not in use (even for a few minutes).
Temperature: The ambient temperature will affect any digital device as well as any digital camera in regard to image quality, this is the nature of any CCD and it's effect on the pixels.
ISO: Changing the ISO setting and doubling the value will half the recommended exposure time. This can be used to avoid hot pixels. This is also only recommended and a general guide. For example; ISO 50 - 60 sec. exposure ISO 100 - 30 sec. exposure ISO 200 etc, However it should be noted that with Higher ISO settings there is higher general noise, so this workaround should be used in balance with the circumstances of the shot.
Why a P45+ instead of a P65+/P40+ and IQ units? If the job calls for images absolutely free of hot pixels and requires long exposure times the P45+ is still a fantastic Digital Back based on the well known noise free exposures up to 1 hour. In general a P 45+ back will provide a noise free capture until 60 minutes. The P 65+ will provide noise free captures up to 60 seconds depending on the heat the back is subject to.